Punkaiser wrote:This is the reason I thought about that, if we don't eat in time our brain will start to alert us with a hungry signal, and if we still insist to not getting any food, after a while our stomach will still keep grinding nothing but itself, lack of ernergy damage the nerves->the brain and all other organs, even muscle to be affected. So I think stomach ache and organ disfunction are all diseases, aren't they? Then true runes are supposed to cure all these internal problems.
I guess it depends on how you define disease. If you consider it to be anything that causes symptoms of discomfort then you might be able to say that. But I think there's evidence that the true rune doesn't prevent disease-like symptoms - remember when Luc showed Sasarai the "clone parts"? He was incapacitated, seemed like he was nauseous, as if he felt like vomiting.
I take the true rune's role to protect from external infection of any sort and prevent cellular breakdown (aging, cancer, auto-immune, etc..).. not to remove the body's internal response to physiological or psychological conditions. I also don't think they remove sense of pain and what have you, and they definitely don't cause you to heal from injury better than anyone else. Even if it did nullify the symptoms of hunger you'd still die, or at least go into some kind of lower energy state. The true rune would have to be actively feeding you, and if this is the case I'd think the bearer wouldn't get hungry and wouldn't bother eating normally (especially if they'd just get fat if none of it would be converted into energy!).. this is the kind of thing you think you'd notice in the games. You'd also expect they wouldn't need sleep and this is something else you think would stand out.